ea0022p519 | Male reproduction | ECE2010
Gavella Mirjana
, Lipovac Vaskresenija
, Antica Mariastefania
, Garaj-Vrhovac Verica
Recent studies have reported that gangliosides, the sialic acid containing glycosphingolipids, are able to modulate many cellular functions. As reactive oxygen species (ROS) in human semen originate from both spermatozoa and infiltrating leukocytes, we aimed to investigate i) the ability of gangliosides to protect human spermatozoa from hydrogen peroxide (H2O2)-induced DNA and membrane damage and ii) the effect of gangliosides on the production of ROS by ...